Version 5.4
Homo sapiens Gene: SPAG11A
Summary
InnateDB Gene IDBG-6653.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPAG11A
Gene Name sperm associated antigen 11A
Synonyms EDDM2B; EP2; EP2C; EP2D; HE2; HE2C; SPAG11
Species Homo sapiens
Ensembl Gene ENSG00000178287
Encoded Proteins
IDBP-6655
sperm associated antigen 11A
IDBP-6657
sperm associated antigen 11A
IDBP-6661
sperm associated antigen 11A
IDBP-228986
sperm associated antigen 11A
IDBP-360797
sperm associated antigen 11A
IDBP-360799
sperm associated antigen 11A
IDBP-592422
sperm associated antigen 11A
IDBP-588224
sperm associated antigen 11A
IDBP-813701
sperm associated antigen 11A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:7847876-7868867
Strand Forward strand
Band p23.1
Transcripts
ENST00000326558 ENSP00000316012
ENST00000351436 ENSP00000297496
ENST00000326625 ENSP00000316648
ENST00000400125 ENSP00000382990
ENST00000434307 ENSP00000416991
ENST00000454911 ENSP00000394885
ENST00000528033 ENSP00000436043
ENST00000525884 ENSP00000434968
ENST00000621858 ENSP00000481649
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006952 defense response
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000059463
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.610978
RefSeq NM_001081552 XM_005272392 XM_005272393
HUGO
OMIM
CCDS CCDS43700
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca