Homo sapiens Gene: UVSSA
Summary
InnateDB Gene IDBG-6670.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UVSSA
Gene Name UV-stimulated scaffold protein A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000163945
Encoded Proteins
KIAA1530
KIAA1530
KIAA1530
KIAA1530
KIAA1530
KIAA1530
Protein Structure
Entrez Gene
Summary The protein encoded by this gene appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex to help repair UV-induced DNA damage. Defects in this gene can cause UV-sensitive syndrome 3. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:1347266-1388049
Strand Forward strand
Band p16.3
Transcripts
ENST00000389851 ENSP00000374501
ENST00000511216 ENSP00000425130
ENST00000507531 ENSP00000421741
ENST00000505716
ENST00000511563 ENSP00000423340
ENST00000512728 ENSP00000427701
ENST00000503548 ENSP00000422795
ENST00000507422
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000993 RNA polymerase II core binding
GO:0005515 protein binding
Biological Process
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0009411 response to UV
GO:0016567 protein ubiquitination
Cellular Component
GO:0005694 chromosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt Q2YD98
TrEMBL Q69YU2
UniProt Splice Variant
Entrez Gene 57654
UniGene Hs.380475
RefSeq NM_020894 XM_005272290 XM_006713897 XM_006713899
HUGO HGNC:29304
OMIM 614632
CCDS CCDS33938
HPRD 17216
IMGT
EMBL AB040963 AC078852 AC118281 AK292661 AL390128 BC021930 BC110331 BC140901
GenPept AAH21930 AAI10332 AAI40902 BAA96054 BAF85350 CAH10662
ImmGen UVSSA (murine)
RNA Seq Atlas 57654