Version 5.4
Homo sapiens Gene: UVSSA
Summary
InnateDB Gene IDBG-6670.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UVSSA
Gene Name UV-stimulated scaffold protein A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000163945
Encoded Proteins
IDBP-6672
KIAA1530
IDBP-479952
KIAA1530
IDBP-482751
KIAA1530
IDBP-477617
KIAA1530
IDBP-476314
KIAA1530
IDBP-477652
KIAA1530
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex to help repair UV-induced DNA damage. Defects in this gene can cause UV-sensitive syndrome 3. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:1347266-1388049
Strand Forward strand
Band p16.3
Transcripts
ENST00000389851 ENSP00000374501
ENST00000511216 ENSP00000425130
ENST00000507531 ENSP00000421741
ENST00000505716
ENST00000511563 ENSP00000423340
ENST00000512728 ENSP00000427701
ENST00000503548 ENSP00000422795
ENST00000507422
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000993 RNA polymerase II core binding
GO:0005515 protein binding
Biological Process
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0009411 response to UV
GO:0016567 protein ubiquitination
Cellular Component
GO:0005694 chromosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037355
View Gene Order
ENSBTAG00000012577
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.380475
RefSeq NM_020894 XM_005272290 XM_006713897 XM_006713899
HUGO
OMIM
CCDS CCDS33938
HPRD 17216
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca