Version 5.4
| Homo sapiens Gene: CCNB3 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-67068.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | CCNB3 | ||||||||||||||||||
| Gene Name | cyclin B3 | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000147082 | ||||||||||||||||||
| Encoded Proteins |
cyclin B3
cyclin B3
cyclin B3
cyclin B3
cyclin B3
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome X:50202713-50351910 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | p11.22 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME | |||||||||||||||||||
| KEGG |
Cell cycle pathway
p53 signaling pathway pathway
Progesterone-mediated oocyte maturation pathway
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| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | Q8WWL7 | ||||||||||||||||||
| TrEMBL | Q8WTR6 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 85417 | ||||||||||||||||||
| UniGene | Hs.130310 Hs.722420 Hs.722421 Hs.740165 | ||||||||||||||||||
| RefSeq | NM_033031 NM_033670 XM_006724610 | ||||||||||||||||||
| HUGO | HGNC:18709 | ||||||||||||||||||
| OMIM | 300456 | ||||||||||||||||||
| CCDS | CCDS14332 CCDS14331 | ||||||||||||||||||
| HPRD | 02350 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AJ314764 AJ314765 AJ314766 AJ416458 AJ421672 AJ421673 AJ421674 AL137550 AL591367 BX323840 CH471180 | ||||||||||||||||||
| GenPept | CAB70806 CAC40024 CAC40025 CAC40026 CAC94915 CAD18845 CAD18846 CAD18847 CAI41320 CAI41321 CAI43220 CAI43221 EAW89922 EAW89923 | ||||||||||||||||||
| RNA Seq Atlas | 85417 | ||||||||||||||||||