Version 5.4
Homo sapiens Gene: RABL2A
Summary
InnateDB Gene IDBG-67266.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RABL2A
Gene Name RAB, member of RAS oncogene family-like 2A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000144134
Encoded Proteins
IDBP-67268
RAB, member of RAS oncogene family-like 2A
IDBP-244169
RAB, member of RAS oncogene family-like 2A
IDBP-244171
RAB, member of RAS oncogene family-like 2A
IDBP-244173
RAB, member of RAS oncogene family-like 2A
IDBP-294638
RAB, member of RAS oncogene family-like 2A
IDBP-294635
RAB, member of RAS oncogene family-like 2A
IDBP-385011
RAB, member of RAS oncogene family-like 2A
IDBP-385012
RAB, member of RAS oncogene family-like 2A
IDBP-385013
RAB, member of RAS oncogene family-like 2A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the RAB gene family which belongs to the RAS GTPase superfamily. The proteins in the family of RAS-related signaling molecules are small GTP-binding proteins that play important roles in the regulation of exocytotic and endocytotic pathways. This gene maps to the site of an ancestral telomere fusion event and may be a subtelomeric gene. Two alternatively spliced transcript variants have been identified, both encoding the same protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:113627229-113643396
Strand Forward strand
Band q14.1
Transcripts
ENST00000376439 ENSP00000365622
ENST00000393167 ENSP00000376872
ENST00000393166 ENSP00000376871
ENST00000393165 ENSP00000376870
ENST00000409842 ENSP00000386460
ENST00000409875 ENSP00000387229
ENST00000409121
ENST00000413545 ENSP00000388944
ENST00000450954 ENSP00000399360
ENST00000452831 ENSP00000415510
ENST00000467600
ENST00000465711
ENST00000493876
ENST00000476236
ENST00000477218
ENST00000478880
ENST00000494909
ENST00000486403
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022621
View Gene Order
ENSBTAG00000004876
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.446425
RefSeq NM_007082 NM_013412 XM_005263569 XM_005263570 XM_005263575 XM_005263576 XM_005263579 XM_006712208 XM_006712209 XM_006712210 XM_006712220
HUGO
OMIM
CCDS CCDS2118
HPRD 10394
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca