Version 5.4
Homo sapiens Gene: SSX7
Summary
InnateDB Gene IDBG-68980.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SSX7
Gene Name synovial sarcoma, X breakpoint 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000187754
Encoded Proteins
IDBP-68927
synovial sarcoma, X breakpoint 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:52644090-52654900
Strand Reverse strand
Band p11.22
Transcripts
ENST00000298181 ENSP00000298181
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q7RTT5
TrEMBL A0A024R019
UniProt Splice Variant
Entrez Gene 280658
UniGene Hs.558712
RefSeq NM_173358
HUGO HGNC:19653
OMIM 300542
CCDS CCDS14343
HPRD
IMGT
EMBL AL450023 BK000687 CH471266
GenPept CAI41147 DAA00374 EAW55864 EAW55865
RNA Seq Atlas 280658

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca