Homo sapiens Gene: MRPL38
Summary
InnateDB Gene IDBG-69087.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRPL38
Gene Name mitochondrial ribosomal protein L38
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000204316
Encoded Proteins
mitochondrial ribosomal protein L38
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:75898643-75905413
Strand Reverse strand
Band q25.1
Transcripts
ENST00000309352 ENSP00000308275
ENST00000410030
ENST00000486101
ENST00000480203
ENST00000483393
ENST00000477371
ENST00000477023
ENST00000471434
ENST00000477736
ENST00000493104
ENST00000494179
ENST00000493383
ENST00000474548
ENST00000461602
ENST00000464758
ENST00000585475
ENST00000588620
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 42 experimentally validated interaction(s) in this database.
Experimentally validated
Total 42 [view]
Protein-Protein 42 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005739 mitochondrion
GO:0005840 ribosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q96DV4
TrEMBL B2R894 B3KN96
UniProt Splice Variant
Entrez Gene 64978
UniGene
RefSeq NM_032478
HUGO HGNC:14033
OMIM 611844
CCDS CCDS11733
HPRD 14758
IMGT
EMBL AB051345 AC087289 AF161380 AK024058 AK313283 BC013311 CH471099
GenPept AAF28940 AAH13311 BAB54935 BAG36091 BAG51258 EAW89339
RNA Seq Atlas 64978