Version 5.4
Homo sapiens Gene: UBE2O
Summary
InnateDB Gene IDBG-69677.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBE2O
Gene Name ubiquitin-conjugating enzyme E2O
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000175931
Encoded Proteins
IDBP-69679
ubiquitin-conjugating enzyme E2O
IDBP-764168
IDBP-761658
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:76389451-76453206
Strand Reverse strand
Band q25.1
Transcripts
ENST00000319380 ENSP00000323687
ENST00000590658 ENSP00000467623
ENST00000587581
ENST00000586409
ENST00000586505
ENST00000587127 ENSP00000468498
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 36 [view]
Protein-Protein 36 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016881 acid-amino acid ligase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006513 protein monoubiquitination
GO:0030513 positive regulation of BMP signaling pathway
GO:0042147 retrograde transport, endosome to Golgi
GO:0070534 protein K63-linked ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020802
View Gene Order
ENSBTAG00000020115
Not yet available
Pathways
NETPATH
NetPath_24
TSLP pathway
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
hsa04120
Ubiquitin mediated proteolysis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.16130
RefSeq NM_022066 XM_005257567
HUGO
OMIM
CCDS CCDS32742
HPRD 10928
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca