Version 5.4
Homo sapiens Gene: HBM
Summary
InnateDB Gene IDBG-7014.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HBM
Gene Name hemoglobin, mu
Synonyms HBAP2; HBK
Species Homo sapiens
Ensembl Gene ENSG00000206177
Encoded Proteins
IDBP-7016
hemoglobin, mu
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. This gene has an ORF encoding a 141 aa polypeptide which is similar to the delta globins found in reptiles and birds. This locus was originally described as a pseudogene; however, it is currently thought to be a protein-coding gene. [provided by RefSeq, Jul 2008]
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5\'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3\'. This gene has an ORF encoding a 141 aa polypeptide which is similar to the delta globins found in reptiles and birds. This locus was originally described as a pseudogene; however, it is currently thought to be a protein-coding gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:153892-166768
Strand Forward strand
Band p13.3
Transcripts
ENST00000356815 ENSP00000349270
ENST00000472539
ENST00000496585
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005344 oxygen transporter activity
GO:0005506 iron ion binding
GO:0019825 oxygen binding
GO:0020037 heme binding
Biological Process
GO:0015671 oxygen transport
Cellular Component
GO:0005833 hemoglobin complex
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.647389
RefSeq NM_001003938
HUGO
OMIM
CCDS CCDS32347
HPRD 13633
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca