Version 5.4
Mus musculus Gene: SYNE1
Summary
InnateDB Gene IDBG-702914.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYNE1
Gene Name Nesprin-1
Synonyms 8B; A330049M09Rik; BE692247; C130039F11Rik; CPG2; mKIAA1756; Myne1
Species Mus musculus
Ensembl Gene ENSMUSG00000096054
Encoded Proteins
IDBP-130558
synaptic nuclear envelope 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:5020203-5550692
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000041639 ENSMUSP00000039440
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005521 lamin binding
GO:0042803 protein homodimerization activity
GO:0044822 poly(A) RNA binding
GO:0051015 actin filament binding
Biological Process
GO:0007030 Golgi organization
GO:0040023 establishment of nucleus localization
GO:0042692 muscle cell differentiation
GO:0090286 cytoskeletal anchoring at nuclear membrane
GO:0090292 nuclear matrix anchoring at nuclear membrane
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005640 nuclear outer membrane
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005856 cytoskeleton
GO:0016021 integral component of membrane
GO:0030017 sarcomere
GO:0031965 nuclear membrane
GO:0034993 SUN-KASH complex
GO:0045211 postsynaptic membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_75800
Meiotic Synapsis pathway
REACT_200794
Mus musculus biological processes pathway
REACT_198626
Meiotic synapsis pathway
REACT_188804
Cell Cycle pathway
REACT_198624
Meiosis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q6ZWR6
TrEMBL Q0VGB8 Q6ZWR5 Q6ZWS6 Q6ZWT2 Q80T95
UniProt Splice Variant
Entrez Gene 64009
UniGene Mm.470643
RefSeq NM_001079686 NM_022027 NM_153399
OMIM
CCDS CCDS56679 CCDS56680
HPRD
IMGT
MGI ID MGI:1927152
MGI Symbol Syne1
EMBL AC156392 AC156393 AC157020 AC159748 AC161829 AC162381 AC162385 AF281869 AF281870 AF535143 AK028641 AK032502 AK036828 AK039486 AK122550 BC110428
GenPept AAG24392 AAG24393 AAI10429 AAN03487 BAC26044 BAC27900 BAC29595 BAC30365 BAC65832
RNA Seq Atlas 64009

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca