Version 5.4
Homo sapiens Gene: PPP6R1
Summary
InnateDB Gene IDBG-70454.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP6R1
Gene Name protein phosphatase 6, regulatory subunit 1
Synonyms KIAA1115; PP6R1; SAP190; SAPS1
Species Homo sapiens
Ensembl Gene ENSG00000105063
Encoded Proteins
IDBP-385338
protein phosphatase 6, regulatory subunit 1
IDBP-764589
IDBP-766128
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:55229780-55258995
Strand Reverse strand
Band q13.42
Transcripts
ENST00000412770 ENSP00000414202
ENST00000592242 ENSP00000466332
ENST00000591323
ENST00000589343
ENST00000586690
ENST00000587457
ENST00000587283 ENSP00000467521
ENST00000591602
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 64 experimentally validated interaction(s) in this database.
Experimentally validated
Total 64 [view]
Protein-Protein 64 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0019903 protein phosphatase binding
Biological Process
GO:0043666 regulation of phosphoprotein phosphatase activity
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000052296
View Gene Order
ENSBTAG00000021157
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.515610
RefSeq NM_014931 XM_005258669 XM_005258670 XM_006723090
HUGO
OMIM
CCDS CCDS46186
HPRD 17207
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca