Version 5.4
Mus musculus Gene: Sox1
Summary
InnateDB Gene IDBG-706410.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sox1
Gene Name SRY-box containing gene 1
Synonyms BB176347; Sox-1
Species Mus musculus
Ensembl Gene ENSMUSG00000096014
Encoded Proteins
IDBP-716891
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182968:
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:12395295-12400126
Strand Forward strand
Band A1.1
Transcripts
ENSMUST00000180353 ENSMUSP00000137203
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001046 core promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001764 neuron migration
GO:0002089 lens morphogenesis in camera-type eye
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0021521 ventral spinal cord interneuron specification
GO:0021879 forebrain neuron differentiation
GO:0021884 forebrain neuron development
GO:0030900 forebrain development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000182968
View Gene Order
ENSBTAG00000038272
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_8
Wnt pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt P53783
TrEMBL
UniProt Splice Variant
Entrez Gene 20664
UniGene Mm.39088
RefSeq NM_009233
OMIM
CCDS CCDS57605
HPRD
IMGT
MGI ID MGI:98357
MGI Symbol Sox1
EMBL AB108672 AC102525 X94126
GenPept BAC75667 CAA63846
RNA Seq Atlas 20664

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca