Version 5.4
Homo sapiens Gene: BTG4
Summary
InnateDB Gene IDBG-70797.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BTG4
Gene Name B-cell translocation gene 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000137707
Encoded Proteins
IDBP-70799
B-cell translocation gene 4
IDBP-383016
B-cell translocation gene 4
IDBP-586347
B-cell translocation gene 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein can induce G1 arrest in the cell cycle. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:111467526-111512354
Strand Reverse strand
Band q23.1
Transcripts
ENST00000356018 ENSP00000348300
ENST00000456861 ENSP00000392358
ENST00000525791 ENSP00000432018
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007050 cell cycle arrest
GO:0008285 negative regulation of cell proliferation
GO:0030182 neuron differentiation
GO:0045930 negative regulation of mitotic cell cycle
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032056
View Gene Order
ENSBTAG00000034346
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03018
RNA degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.128180 Hs.734027
RefSeq NM_017589
HUGO
OMIM
CCDS CCDS8346
HPRD 16138
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca