Version 5.4
Homo sapiens Gene: SIK2
Summary
InnateDB Gene IDBG-70866.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SIK2
Gene Name salt-inducible kinase 2
Synonyms LOH11CR1I; QIK; SNF1LK2
Species Homo sapiens
Ensembl Gene ENSG00000170145
Encoded Proteins
IDBP-70868
salt-inducible kinase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:111602391-111730853
Strand Forward strand
Band q23.1
Transcripts
ENST00000304987 ENSP00000305976
ENST00000533868
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0008286 insulin receptor signaling pathway
GO:0035556 intracellular signal transduction
GO:0046626 regulation of insulin receptor signaling pathway
GO:0046777 protein autophosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037112
View Gene Order
ENSBTAG00000020272
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
lkb1_pathway
LKB1 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.594110 Hs.734511
RefSeq NM_015191
HUGO
OMIM
CCDS CCDS8347
HPRD 12348
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca