Version 5.4
Homo sapiens Gene: FXC1
Summary
InnateDB Gene IDBG-710770.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FXC1
Gene Name Fracture callus 1 homolog (Rat); cDNA FLJ11268 fis, clone PLACE1009186, highly similar to Mitochondrial import inner membrane translocase subunit Tim9B; cDNA, FLJ92024, Homo sapiens fracture callus 1 homolog (rat) (FXC1), mRNA
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000265264
Encoded Proteins
IDBP-485306
fracture callus 1 homolog (rat)
IDBP-479070
fracture callus 1 homolog (rat)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary FXC1, or TIMM10B, belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM, Apr 2004]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:6481485-6508978
Strand Forward strand
Band p15.4
Transcripts
ENST00000464330 ENSP00000419490
ENST00000472836 ENSP00000419704
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
GO:0006626 protein targeting to mitochondrion
GO:0007160 cell-matrix adhesion
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0005758 mitochondrial intermembrane space
GO:0042719 mitochondrial intermembrane space protein transporter complex
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO
OMIM
CCDS CCDS7766
HPRD 16242
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca