Homo sapiens Gene: ITIH6
Summary
InnateDB Gene IDBG-71471.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ITIH6
Gene Name inter-alpha-trypsin inhibitor heavy chain family, member 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000102313
Encoded Proteins
inter-alpha (globulin) inhibitor H5-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the interalpha trypsin inhibitor heavy chain (ITIH) family. Interalpha trypsin inhibitor (ITI) is composed of two heavy chains (containing VWA domain) and one light chain. The light chain confers the protease-inhibitor function, while the heavy chains are involved in mediating protein-protein interactions with the components of the extracellular matrix. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:54748899-54798240
Strand Reverse strand
Band p11.22
Transcripts
ENST00000218436 ENSP00000218436
ENST00000498398
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
GO:0030212 hyaluronan metabolic process
Cellular Component
GO:0005576 extracellular region
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q6UXX5
TrEMBL
UniProt Splice Variant
Entrez Gene 347365
UniGene Hs.454272
RefSeq NM_198510
HUGO HGNC:28907
OMIM
CCDS CCDS14361
HPRD 17164
IMGT
EMBL AL022575 AY358170 CH471154 Z98046
GenPept AAQ88537 CAI42344 CAI42356 EAW93186
RNA Seq Atlas 347365