Version 5.4
Homo sapiens Gene: ANKK1
Summary
InnateDB Gene IDBG-71665.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANKK1
Gene Name ankyrin repeat and kinase domain containing 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170209
Encoded Proteins
IDBP-71667
ankyrin repeat and kinase domain containing 1
IDBP-595534
ankyrin repeat and kinase domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:113387791-113400418
Strand Forward strand
Band q23.2
Transcripts
ENST00000303941 ENSP00000306678
ENST00000542948 ENSP00000445810
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032257
View Gene Order
ENSBTAG00000010855
Not yet available
Cross-References
SwissProt Q8NFD2
TrEMBL
UniProt Splice Variant
Entrez Gene 255239
UniGene Hs.448473
RefSeq NM_178510 XM_006718809 XM_006718810
HUGO HGNC:21027
OMIM 608774
CCDS CCDS44734
HPRD
IMGT
EMBL AF487542 AF525298 AJ541797
GenPept AAM91924 AAQ09005 CAD62569
RNA Seq Atlas 255239

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca