Version 5.4
Homo sapiens Gene: CADM1
Summary
InnateDB Gene IDBG-72227.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CADM1
Gene Name cell adhesion molecule 1
Synonyms BL2; IGSF4; IGSF4A; Necl-2; NECL2; RA175; sgIGSF; ST17; sTSLC-1; SYNCAM; synCAM1; TSLC1
Species Homo sapiens
Ensembl Gene ENSG00000182985
Encoded Proteins
IDBP-72231
cell adhesion molecule 1
IDBP-383295
cell adhesion molecule 1
IDBP-602911
cell adhesion molecule 1
IDBP-601204
cell adhesion molecule 1
IDBP-583722
cell adhesion molecule 1
IDBP-585537
cell adhesion molecule 1
IDBP-592174
cell adhesion molecule 1
IDBP-595802
cell adhesion molecule 1
IDBP-587259
cell adhesion molecule 1
IDBP-583291
cell adhesion molecule 1
IDBP-584627
cell adhesion molecule 1
IDBP-811661
cell adhesion molecule 1
IDBP-811665
cell adhesion molecule 1
IDBP-811667
cell adhesion molecule 1
IDBP-811668
cell adhesion molecule 1
IDBP-811669
cell adhesion molecule 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:115169218-115504957
Strand Reverse strand
Band q23.3
Transcripts
ENST00000331581 ENSP00000329797
ENST00000441886
ENST00000452722 ENSP00000395359
ENST00000545960
ENST00000537140
ENST00000542447 ENSP00000439176
ENST00000537058 ENSP00000439817
ENST00000536727 ENSP00000440322
ENST00000545380 ENSP00000442387
ENST00000546000
ENST00000543375
ENST00000540852
ENST00000541434
ENST00000540373
ENST00000542450 ENSP00000442001
ENST00000543540 ENSP00000439847
ENST00000545094 ENSP00000439696
ENST00000543249 ENSP00000442227
ENST00000540951 ENSP00000445375
ENST00000536781
ENST00000621709 ENSP00000482924
ENST00000612235 ENSP00000483648
ENST00000616271 ENSP00000484516
ENST00000612471 ENSP00000483793
ENST00000621043 ENSP00000482840
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0030165 PDZ domain binding
GO:0042803 protein homodimerization activity
GO:0050839 cell adhesion molecule binding
Biological Process
GO:0001889 liver development
GO:0006915 apoptotic process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion
GO:0007157 heterophilic cell-cell adhesion
GO:0007283 spermatogenesis
GO:0007416 synapse assembly
GO:0007420 brain development
GO:0008037 cell recognition
GO:0009826 unidimensional cell growth
GO:0016338 calcium-independent cell-cell adhesion
GO:0030154 cell differentiation
GO:0034329 cell junction assembly
GO:0034332 adherens junction organization
GO:0042271 susceptibility to natural killer cell mediated cytotoxicity
GO:0045216 cell-cell junction organization
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0050715 positive regulation of cytokine secretion
GO:0051606 detection of stimulus
GO:0060348 bone development
Cellular Component
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0008021 synaptic vesicle
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0030424 axon
GO:0030425 dendrite
GO:0043005 neuron projection
GO:0045202 synapse
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032076
View Gene Order
ENSBTAG00000000977
Not yet available
Pathways
NETPATH
REACTOME
REACT_19268
Nectin/Necl trans heterodimerization pathway
REACT_19195
Adherens junctions interactions pathway
REACT_111155
Cell-Cell communication pathway
REACT_20676
Cell junction organization pathway
REACT_19331
Cell-cell junction organization pathway
KEGG
hsa04514
Cell adhesion molecules (CAMs) pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F5H0H5 F5H8J9 Q6MZK6
UniProt Splice Variant
Entrez Gene 23705
UniGene
RefSeq NM_001098517 NM_001301043 NM_001301044 NM_001301045 NM_014333 XM_005271491 XM_005271492 XM_005271493
HUGO HGNC:5951
OMIM 605686
CCDS CCDS53711 CCDS73397 CCDS73398 CCDS73399 CCDS8373
HPRD
IMGT
EMBL AP000462 AP000465 AP003174 AP003179 AP005020 BX641042
GenPept CAE46024
RNA Seq Atlas 23705

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca