InnateDB Gene
|
IDBG-726260.2
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
TEN1-CDK3
|
Gene Name
|
TEN1-CDK3 readthrough (non-protein coding)
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Gene
|
ENSG00000261408
|
Encoded Proteins
|
|
Protein Structure
|
|
Useful resources
|
Stemformatics
EHFPI
ImmGen
|
Summary |
This locus represents naturally occurring read-through transcription between the neighboring TEN1 telomerase capping complex subunit homolog (S. cerevisiae) and cyclin-dependent kinase 3 (CDK3) genes. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is therefore unlikely to produce a protein product. [provided by RefSeq, Oct 2011]
This gene encodes a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. [provided by RefSeq, Jul 2008]
|
Type |
Protein coding
|
Genomic Location
|
Chromosome 17:75979231-76005999
|
Strand
|
Forward strand
|
Band
|
q25.1
|
Transcripts
|
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
Molecular Function |
Accession |
GO Term |
GO:0004672
|
protein kinase activity
|
GO:0004674
|
protein serine/threonine kinase activity
|
GO:0004693
|
cyclin-dependent protein serine/threonine kinase activity
|
GO:0004713
|
protein tyrosine kinase activity
|
GO:0005524
|
ATP binding
|
GO:0016772
|
transferase activity, transferring phosphorus-containing groups
|
|
Biological Process |
|
Cellular Component |
|
|
No orthologs found for this gene |
SwissProt
|
|
TrEMBL
|
|
UniProt Splice Variant
|
|
Entrez Gene
|
|
UniGene
|
Hs.706766
|
RefSeq
|
NM_001258
|
HUGO
|
|
OMIM
|
|
CCDS
|
CCDS11736
|
HPRD |
|
IMGT
|
|
EMBL
|
|
GenPept
|
|
RNA Seq Atlas
|
|
|
|