Homo sapiens Gene: APOC4
Summary
InnateDB Gene IDBG-729588.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APOC4
Gene Name apolipoprotein C-IV
Synonyms APO-CIV; APOC-IV
Species Homo sapiens
Ensembl Gene ENSG00000267467
Encoded Proteins
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene. [provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:44942238-44945496
Strand Forward strand
Band q13.32
Transcripts
ENST00000591600 ENSP00000466444
ENST00000592954 ENSP00000468236
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005319 lipid transporter activity
Biological Process
GO:0006629 lipid metabolic process
GO:0006869 lipid transport
GO:0010890 positive regulation of sequestering of triglyceride
GO:0070328 triglyceride homeostasis
Cellular Component
GO:0034361 very-low-density lipoprotein particle
GO:0034364 high-density lipoprotein particle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt P55056
TrEMBL K7EMC3
UniProt Splice Variant
Entrez Gene 346
UniGene
RefSeq NM_001646
HUGO HGNC:611
OMIM 600745
CCDS CCDS12649
HPRD 02848
IMGT
EMBL AC011481 AK126257 AY422953 BC020723 CH471126 U32576
GenPept AAA91653 AAH20723 AAQ91812 BAG54298 EAW57310
RNA Seq Atlas 346