Version 5.4
Homo sapiens Gene: ZIM2
Summary
InnateDB Gene IDBG-730683.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZIM2
Gene Name zinc finger, imprinted 2
Synonyms ZNF656
Species Homo sapiens
Ensembl Gene ENSG00000269699
Encoded Proteins
IDBP-765000
IDBP-762820
IDBP-762311
IDBP-764348
IDBP-765773
IDBP-764188
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary In human, ZIM2 and PEG3 (GeneID:5178) are two distinct genes that share a set of 5' exons and have a common promoter, and both genes are paternally expressed. Alternative splicing events connect the shared exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. This is in contrast to mouse and cow, where ZIM2 and PEG3 genes do not share exons in common, and the imprinting status of ZIM2 is also not conserved amongst mammals. Additional 5' alternatively spliced transcripts encoding the same protein have been found for the human ZIM2 gene. [provided by RefSeq, Oct 2010]
In human, ZIM2 and PEG3 (GeneID:5178) are two distinct genes that share a set of 5\' exons and have a common promoter, and both genes are paternally expressed. Alternative splicing events connect the shared exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. This is in contrast to mouse and cow, where ZIM2 and PEG3 genes do not share exons in common, and the imprinting status of ZIM2 is also not conserved amongst mammals. Additional 5\' alternatively spliced transcripts encoding the same protein have been found for the human ZIM2 gene. [provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:56774552-56840729
Strand Reverse strand
Band q13.43
Transcripts
ENST00000597281 ENSP00000471643
ENST00000593711 ENSP00000472306
ENST00000599935 ENSP00000468984
ENST00000593931 ENSP00000469173
ENST00000595671 ENSP00000469185
ENST00000601070 ENSP00000470326
ENST00000596270
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005575 cellular_component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_12627
Generic Transcription Pathway pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL M0R155
UniProt Splice Variant
Entrez Gene 23619
UniGene Hs.610582
RefSeq NM_001146326 NM_001146327 NM_015363
HUGO HGNC:12875
OMIM
CCDS CCDS33123
HPRD 10321
IMGT
EMBL AC006115
GenPept
RNA Seq Atlas 23619

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca