Version 5.4
Homo sapiens Gene: CD7
Summary
InnateDB Gene IDBG-73437.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD7
Gene Name CD7 molecule
Synonyms GP40; LEU-9; Tp40; TP41
Species Homo sapiens
Ensembl Gene ENSG00000173762
Encoded Proteins
IDBP-73439
CD7 molecule
IDBP-761443
IDBP-762816
IDBP-762068
IDBP-762385
IDBP-762527
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:82314868-82317602
Strand Reverse strand
Band q25.3
Transcripts
ENST00000312648 ENSP00000312027
ENST00000584284 ENSP00000463612
ENST00000578509 ENSP00000464565
ENST00000581744
ENST00000582480 ENSP00000464182
ENST00000583376 ENSP00000463489
ENST00000581434 ENSP00000464546
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0006955 immune response
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0042110 T cell activation
GO:0048873 homeostasis of number of cells within a tissue
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
NetPath_11
TCR pathway
REACTOME
KEGG
hsa04640
Hematopoietic cell lineage pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.36972
RefSeq NM_006137
HUGO
OMIM
CCDS CCDS11807
HPRD 01732
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca