Version 5.4
Homo sapiens Gene: SECTM1
Summary
InnateDB Gene IDBG-73454.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SECTM1
Gene Name secreted and transmembrane 1
Synonyms K12
Species Homo sapiens
Ensembl Gene ENSG00000141574
Encoded Proteins
IDBP-73456
secreted and transmembrane 1
IDBP-763686
IDBP-762581
IDBP-760866
IDBP-763169
IDBP-764445
IDBP-761961
IDBP-761480
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a transmembrane and secreted protein with characteristics of a type 1a transmembrane protein. It is found in a perinuclear Golgi-like pattern and thought to be involved in hematopoietic and/or immune system processes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:82321024-82334074
Strand Reverse strand
Band q25.3
Transcripts
ENST00000269389 ENSP00000269389
ENST00000581954 ENSP00000464385
ENST00000582290 ENSP00000462294
ENST00000580437 ENSP00000463904
ENST00000583093 ENSP00000462563
ENST00000581691 ENSP00000463114
ENST00000582563 ENSP00000463120
ENST00000581864 ENSP00000464111
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005125 cytokine activity
Biological Process
GO:0006955 immune response
GO:0007165 signal transduction
GO:0007498 mesoderm development
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Cellular Component
GO:0005615 extracellular space
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.558009
RefSeq NM_003004 XM_005256392
HUGO
OMIM
CCDS CCDS11808
HPRD 04004
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca