Version 5.4
Homo sapiens Gene: FN3K
Summary
InnateDB Gene IDBG-73769.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FN3K
Gene Name fructosamine 3 kinase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000167363
Encoded Proteins
IDBP-73771
fructosamine 3 kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:82735575-82751197
Strand Forward strand
Band q25.3
Transcripts
ENST00000300784 ENSP00000300784
ENST00000573841
ENST00000570734
ENST00000574496
ENST00000572813
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0030387 fructosamine-3-kinase activity
Biological Process
GO:0016310 phosphorylation
GO:0030389 fructosamine metabolic process
GO:0030393 fructoselysine metabolic process
GO:0030855 epithelial cell differentiation
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025175
View Gene Order
ENSBTAG00000015394
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.151135
RefSeq NM_022158
HUGO
OMIM
CCDS CCDS11818
HPRD 16336
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca