Version 5.4
Homo sapiens Gene: RAB41
Summary
InnateDB Gene IDBG-74355.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAB41
Gene Name RAB41, member RAS oncogene family
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000147127
Encoded Proteins
IDBP-74357
RAB41, member RAS oncogene family
IDBP-74359
RAB41, member RAS oncogene family
IDBP-479428
RAB41, member RAS oncogene family
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily. These proteins function as regulators of membrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). This family member can be activated by the GAP protein RN-Tre, and it is localized to the Golgi complex. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:70282093-70285002
Strand Forward strand
Band q13.1
Transcripts
ENST00000374473 ENSP00000363597
ENST00000276066 ENSP00000276066
ENST00000509895 ENSP00000421643
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q5JT25
TrEMBL D6REW8
UniProt Splice Variant
Entrez Gene 347517
UniGene Hs.276327
RefSeq NM_001032726
HUGO HGNC:18293
OMIM
CCDS CCDS35322
HPRD
IMGT
EMBL AL357752 BC117239
GenPept AAI17240 CAI41489
RNA Seq Atlas 347517

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca