Homo sapiens Gene: CTNNBL1
Summary
InnateDB Gene IDBG-74368.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CTNNBL1
Gene Name catenin, beta like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132792
Encoded Proteins
catenin, beta like 1
catenin, beta like 1
catenin, beta like 1
catenin, beta like 1
catenin, beta like 1
catenin, beta like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs. In addition, the encoded protein contains Armadillo/beta-catenin-like repeats, which have been implicated in protein-protein interactions. Although the function of this protein has not been determined, the C-terminal portion of the protein has been shown to possess apoptosis-inducing activity. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:37693955-37872129
Strand Forward strand
Band q11.23
Transcripts
ENST00000361383 ENSP00000355050
ENST00000373473 ENSP00000362572
ENST00000373469 ENSP00000362568
ENST00000405275 ENSP00000384355
ENST00000447935 ENSP00000394464
ENST00000473857
ENST00000472237
ENST00000481674
ENST00000621317 ENSP00000478532
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 58 experimentally validated interaction(s) in this database.
Experimentally validated
Total 58 [view]
Protein-Protein 56 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0019899 enzyme binding
Biological Process
GO:0006397 mRNA processing
GO:0006915 apoptotic process
GO:0008380 RNA splicing
GO:0016445 somatic diversification of immunoglobulins
GO:0043065 positive regulation of apoptotic process
Cellular Component
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
mRNA Splicing - Major Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
mRNA Splicing pathway
Gene Expression pathway
KEGG
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt Q8WYA6
TrEMBL A2A2P1
UniProt Splice Variant
Entrez Gene 56259
UniGene Hs.472667
RefSeq NM_001281495 NM_030877
HUGO HGNC:15879
OMIM 611537
CCDS CCDS13298
HPRD
IMGT
EMBL AF239607 AF367471 AF370431 AK024761 AK074663 AK222592 AK293420 AL023804 AL109964 AL118499 BC022802 BC121005 BC121006
GenPept AAH22802 AAI21006 AAI21007 AAK53407 AAL69567 AAQ15267 BAB14992 BAC11121 BAD96312 BAG56927 CAI19331 CAI19332 CAI42203 CAI42204 CAI42208 CAI42984 CAI42985 CAI42986
RNA Seq Atlas 56259