Version 5.4
Homo sapiens Gene: GDPD2
Summary
InnateDB Gene IDBG-74497.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GDPD2
Gene Name glycerophosphodiester phosphodiesterase domain containing 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000130055
Encoded Proteins
IDBP-74499
glycerophosphodiester phosphodiesterase domain containing 2
IDBP-374774
glycerophosphodiester phosphodiesterase domain containing 2
IDBP-587162
glycerophosphodiester phosphodiesterase domain containing 2
IDBP-595922
glycerophosphodiester phosphodiesterase domain containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the glycerophosphodiester phosphodiesterase enzyme family. The encoded protein hydrolyzes glycerophosphoinositol to produce inositol 1-phosphate and glycerol. This protein may have a role in osteoblast differentiation and growth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:70423031-70433390
Strand Forward strand
Band q13.1
Transcripts
ENST00000374382 ENSP00000363503
ENST00000453994 ENSP00000414019
ENST00000472623
ENST00000536730 ENSP00000445982
ENST00000538649 ENSP00000444601
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008081 phosphoric diester hydrolase activity
GO:0008889 glycerophosphodiester phosphodiesterase activity
GO:0046872 metal ion binding
GO:0047394 glycerophosphoinositol inositolphosphodiesterase activity
Biological Process
GO:0006071 glycerol metabolic process
GO:0006629 lipid metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000019359
View Gene Order
ENSBTAG00000012863
Not yet available
Cross-References
SwissProt Q9HCC8
TrEMBL
UniProt Splice Variant
Entrez Gene 54857
UniGene Hs.438712
RefSeq NM_001171191 NM_001171192 NM_001171193 NM_017711
HUGO HGNC:25974
OMIM
CCDS CCDS14402 CCDS55437 CCDS55438
HPRD
IMGT
EMBL AB048363 AK000214 AK299255 AK301025 AK316035 AL139398 AY358986 BC032009
GenPept AAH32009 AAQ89345 BAA91014 BAB13350 BAG61286 BAG62641 BAH14406 CAI41020
RNA Seq Atlas 54857

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca