Version 5.4
Homo sapiens Gene: PPP1R16B
Summary
InnateDB Gene IDBG-74938.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R16B
Gene Name protein phosphatase 1, regulatory subunit 16B
Synonyms ANKRD4; TIMAP
Species Homo sapiens
Ensembl Gene ENSG00000101445
Encoded Proteins
IDBP-74940
protein phosphatase 1, regulatory subunit 16B
IDBP-74942
protein phosphatase 1, regulatory subunit 16B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:38805705-38923024
Strand Forward strand
Band q11.23
Transcripts
ENST00000299824 ENSP00000299824
ENST00000373331 ENSP00000362428
ENST00000468265
ENST00000463749
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019903 protein phosphatase binding
Biological Process
GO:0007165 signal transduction
GO:0051489 regulation of filopodium assembly
Cellular Component
GO:0005634 nucleus
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037754
View Gene Order
ENSBTAG00000000653
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.45719
RefSeq NM_001172735 NM_015568
HUGO
OMIM
CCDS CCDS13309 CCDS54462
HPRD 15168
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca