Version 5.4
Homo sapiens Gene: TRIM10
Summary
InnateDB Gene IDBG-75741.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM10
Gene Name tripartite motif containing 10
Synonyms HERF1; RFB30; RNF9
Species Homo sapiens
Ensembl Gene ENSG00000204613
Encoded Proteins
IDBP-75745
tripartite motif containing 10
IDBP-368363
tripartite motif containing 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic bodies. Studies in mice suggest that this protein plays a role in terminal differentiation of erythroid cells. Alternate splicing of this gene generates two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:30151945-30160934
Strand Reverse strand
Band p22.1
Transcripts
ENST00000376704 ENSP00000365894
ENST00000449742 ENSP00000397073
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0008150 biological_process
GO:0030218 erythrocyte differentiation
GO:0045087 innate immune response
GO:0046597 negative regulation of viral entry into host cell
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000073400
View Gene Order
ENSBTAG00000007530
Not yet available
Cross-References
SwissProt Q9UDY6
TrEMBL
UniProt Splice Variant
Entrez Gene 10107
UniGene Hs.613209 Hs.709483
RefSeq NM_052828 NM_006778
HUGO HGNC:10072
OMIM 605701
CCDS CCDS4676 CCDS34375
HPRD 05752
IMGT
EMBL AB088089 AB103595 AB202085 AF220122 AF220123 AL669914 AL671859 AL844220 BA000025 BC093926 BC113419 BX005441 BX927221 CH471081 CR753815 CR759838 CR788282 Y07829
GenPept AAG53495 AAG53496 AAH93926 AAI13420 BAB63332 BAC54921 BAE78605 BAF31256 CAB52384 CAI17586 CAI17587 CAI18187 CAI18188 CAI18609 CAI18610 CAM26237 CAM26238 CAP58479 CAP58480 CAQ07456 CAQ07457 CAQ10308 CAQ10309 CAQ11091 CAQ11092 EAX03268 EAX03269
RNA Seq Atlas 10107

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca