Version 5.4
| Homo sapiens Gene: KIRREL3 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-75885.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | KIRREL3 | ||||||
| Gene Name | kin of IRRE like 3 (Drosophila) | ||||||
| Synonyms | |||||||
| Species | Homo sapiens | ||||||
| Ensembl Gene | ENSG00000149571 | ||||||
| Encoded Proteins |
kin of IRRE like 3 (Drosophila)
kin of IRRE like 3 (Drosophila)
kin of IRRE like 3 (Drosophila)
kin of IRRE like 3 (Drosophila)
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| Protein Structure | |||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 11:126423359-127003460 | ||||||
| Strand | Reverse strand | ||||||
| Band | q24.2 | ||||||
| Transcripts | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME |
Nephrin interactions pathway
Cell-Cell communication pathway
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| KEGG | |||||||
| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | |||||||
| TrEMBL | B4DT91 E9PRX9 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 84623 | ||||||
| UniGene | Hs.376015 | ||||||
| RefSeq | NM_001301097 XM_005271702 NM_001161707 NM_032531 | ||||||
| HUGO | HGNC:23204 | ||||||
| OMIM | 607761 | ||||||
| CCDS | CCDS73413 CCDS53723 CCDS55796 | ||||||
| HPRD | 09679 | ||||||
| IMGT | |||||||
| EMBL | AK300108 AP000741 AP000806 AP001783 AP002832 AP002833 | ||||||
| GenPept | BAG61903 | ||||||
| RNA Seq Atlas | 84623 | ||||||