Homo sapiens Gene: TP53AIP1
Summary
InnateDB Gene IDBG-76005.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TP53AIP1
Gene Name tumor protein p53 regulated apoptosis inducing protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000120471
Encoded Proteins
tumor protein p53 regulated apoptosis inducing protein 1
tumor protein p53 regulated apoptosis inducing protein 1
tumor protein p53 regulated apoptosis inducing protein 1
tumor protein p53 regulated apoptosis inducing protein 1
tumor protein p53 regulated apoptosis inducing protein 1
tumor protein p53 regulated apoptosis inducing protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:128934731-128943399
Strand Reverse strand
Band q24.3
Transcripts
ENST00000458238 ENSP00000390694
ENST00000531399 ENSP00000432743
ENST00000525390
ENST00000530777 ENSP00000432908
ENST00000527504 ENSP00000435175
ENST00000602346 ENSP00000473353
ENST00000621818 ENSP00000479350
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 1 [view]
Protein-DNA 6 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006915 apoptotic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
p53 signaling pathway pathway
INOH
PID NCI
p53 pathway
p73 transcription factor network
Cross-References
SwissProt Q9HCN2
TrEMBL A7LAQ2
UniProt Splice Variant
Entrez Gene 63970
UniGene Hs.160953
RefSeq NM_001195194 NM_001195195 NM_001251964 NM_022112
HUGO HGNC:29984
OMIM 605426
CCDS CCDS55797 CCDS55798 CCDS58195 CCDS8480
HPRD
IMGT
EMBL AB045830 AB045831 AB045832 AP000920 AY302135 BC069399 BC069426 EF693749
GenPept AAH69399 AAH69426 AAP57627 ABS42982 BAB16421 BAB16422 BAB16423
RNA Seq Atlas 63970