Version 5.4
Homo sapiens Gene: PRDM10
Summary
InnateDB Gene IDBG-76124.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRDM10
Gene Name PR domain containing 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170325
Encoded Proteins
IDBP-76128
PR domain containing 10
IDBP-76130
PR domain containing 10
IDBP-76132
PR domain containing 10
IDBP-384687
PR domain containing 10
IDBP-597715
PR domain containing 10
IDBP-603257
PR domain containing 10
IDBP-598528
PR domain containing 10
IDBP-590280
PR domain containing 10
IDBP-593522
PR domain containing 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:129899706-130002835
Strand Reverse strand
Band q24.3
Transcripts
ENST00000358825 ENSP00000351686
ENST00000360871 ENSP00000354118
ENST00000304538 ENSP00000302669
ENST00000423662 ENSP00000398431
ENST00000528746 ENSP00000431262
ENST00000526082 ENSP00000432237
ENST00000533431 ENSP00000435940
ENST00000527581 ENSP00000432093
ENST00000531431 ENSP00000436681
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0008168 methyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0032259 methylation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042496
View Gene Order
ENSBTAG00000019001
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.275086
RefSeq NM_020228 NM_199437 NM_199438 NM_199439 XM_006718886
HUGO
OMIM
CCDS CCDS44771 CCDS44772 CCDS8484 CCDS8485
HPRD 11455
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca