Version 5.4
Homo sapiens Gene: TOMM22
Summary
InnateDB Gene IDBG-7682.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TOMM22
Gene Name translocase of outer mitochondrial membrane 22 homolog (yeast)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100216
Encoded Proteins
IDBP-7684
translocase of outer mitochondrial membrane 22 homolog (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:38681948-38685421
Strand Forward strand
Band q13.1
Transcripts
ENST00000216034 ENSP00000216034
ENST00000492561
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
Experimentally validated
Total 29 [view]
Protein-Protein 27 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008320 protein transmembrane transporter activity
Biological Process
GO:0006626 protein targeting to mitochondrion
GO:0006886 intracellular protein transport
GO:0044267 cellular protein metabolic process
GO:0045040 protein import into mitochondrial outer membrane
Cellular Component
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005742 mitochondrial outer membrane translocase complex
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022427
View Gene Order
ENSBTAG00000010157
Not yet available
Pathways
NETPATH
REACTOME
REACT_118595
Mitochondrial protein import pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9NS69
TrEMBL Q549C5
UniProt Splice Variant
Entrez Gene 56993
UniGene Hs.595072
RefSeq NM_020243
HUGO HGNC:18002
OMIM 607046
CCDS CCDS13975
HPRD
IMGT
EMBL AB040119 AB041906 AF163256 AK024731 AK312076 BC009363 CH471095 CR456475
GenPept AAH09363 AAQ13585 BAB03306 BAB14979 BAB16408 BAG35012 CAG30361 EAW60253 EAW60257
RNA Seq Atlas 56993

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca