Version 5.4
Homo sapiens Gene: VARS2
Summary
InnateDB Gene IDBG-76881.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VARS2
Gene Name valyl-tRNA synthetase 2, mitochondrial
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000137411
Encoded Proteins
IDBP-76891
valyl-tRNA synthetase 2, mitochondrial (putative)
IDBP-370199
valyl-tRNA synthetase 2, mitochondrial (putative)
IDBP-370206
valyl-tRNA synthetase 2, mitochondrial (putative)
IDBP-604295
valyl-tRNA synthetase 2, mitochondrial (putative)
IDBP-604297
valyl-tRNA synthetase 2, mitochondrial (putative)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:30908242-30926459
Strand Forward strand
Band p21.33
Transcripts
ENST00000321897 ENSP00000316092
ENST00000428017 ENSP00000403749
ENST00000421263 ENSP00000416390
ENST00000477288
ENST00000467717
ENST00000490699
ENST00000469358
ENST00000476162
ENST00000477052
ENST00000473916
ENST00000541562 ENSP00000441000
ENST00000542001 ENSP00000438200
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0002161 aminoacyl-tRNA editing activity
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004832 valine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006438 valyl-tRNA aminoacylation
GO:0006450 regulation of translational fidelity
GO:0010467 gene expression
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038838
View Gene Order
ENSBTAG00000010698
Not yet available
Pathways
NETPATH
REACTOME
REACT_15302
Mitochondrial tRNA aminoacylation pathway
REACT_15482
tRNA Aminoacylation pathway
REACT_71
Gene Expression pathway
KEGG
hsa00970
Aminoacyl-tRNA biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q5ST30
TrEMBL A2ABL6 B7ZCJ6
UniProt Splice Variant
Entrez Gene 57176
UniGene Hs.597526
RefSeq NM_001167733 NM_001167734 NM_020442
HUGO HGNC:21642
OMIM 612802
CCDS CCDS34387 CCDS54980
HPRD 11670
IMGT
EMBL AB067472 AB209479 AK025618 AK125069 AK293780 AK304807 AL122037 AL662854 AL669830 AL773541 BC008844 BC009355 BC073838 BC112054 BC113605 BX927194 CR759747 CR936875
GenPept AAH08844 AAH09355 AAH73838 AAI12055 AAI13606 BAB15191 BAB67778 BAD92716 BAG57195 BAG65557 CAB59177 CAI17437 CAI18004 CAI18453 CAM24842 CAM25404 CAQ06763 CAQ06764 CAQ09774 CAQ09775 CAQ10925 CAQ10926
RNA Seq Atlas 57176

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca