Version 5.4
Homo sapiens Gene: KIAA2022
Summary
InnateDB Gene IDBG-77243.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KIAA2022
Gene Name KIAA2022
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000050030
Encoded Proteins
IDBP-77247
KIAA2022
IDBP-376077
KIAA2022
IDBP-810060
KIAA2022
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary An inversion on the X chromosome which disrupts this gene and a G-protein coupled purinergic receptor gene located in the pseudoautosomal region of the X chromosome has been linked to X linked mental retardation.[provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:74732849-74925485
Strand Reverse strand
Band q13.3
Transcripts
ENST00000055682 ENSP00000055682
ENST00000424929 ENSP00000407055
ENST00000616200 ENSP00000480284
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003887 DNA-directed DNA polymerase activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006287 base-excision repair, gap-filling
GO:0006297 nucleotide-excision repair, DNA gap filling
GO:0007346 regulation of mitotic cell cycle
GO:0007399 nervous system development
GO:0043137 DNA replication, removal of RNA primer
GO:0045004 DNA replication proofreading
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005634 nucleus
GO:0043625 delta DNA polymerase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000046449
View Gene Order
ENSBTAG00000000300
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 340533
UniGene
RefSeq NM_001008537
HUGO HGNC:29433
OMIM 300524
CCDS CCDS35337
HPRD
IMGT
EMBL AB095942 AL139395 AL390035 AY563507 BC152557
GenPept AAI52558 AAT67985 BAC23118 CAI39510 CAI39511
RNA Seq Atlas 340533

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca