Homo sapiens Gene: WFDC11
Summary
InnateDB Gene IDBG-77910.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WFDC11
Gene Name WAP four-disulfide core domain 11
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000180083
Encoded Proteins
WAP four-disulfide core domain 11
WAP four-disulfide core domain 11
WAP four-disulfide core domain 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:45648563-45670270
Strand Reverse strand
Band q13.12
Transcripts
ENST00000356562 ENSP00000348968
ENST00000324384 ENSP00000318753
ENST00000618797 ENSP00000479579
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 0
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005576 extracellular region
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 259239
UniGene
RefSeq NM_147197
HUGO HGNC:20478
OMIM
CCDS CCDS13364
HPRD
IMGT
EMBL AL031671 AY047609 BC062670 CH471077
GenPept AAH62670 AAK97771 CAI22435 EAW75824 EAW75825
RNA Seq Atlas 259239