Homo sapiens Gene: WFDC10B | |||||
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Summary | |||||
InnateDB Gene | IDBG-77920.6 | ||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
Gene Symbol | WFDC10B | ||||
Gene Name | WAP four-disulfide core domain 10B | ||||
Synonyms | |||||
Species | Homo sapiens | ||||
Ensembl Gene | ENSG00000182931 | ||||
Encoded Proteins |
WAP four-disulfide core domain 10B
WAP four-disulfide core domain 10B
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Protein Structure | |||||
Useful resources | Stemformatics EHFPI ImmGen | ||||
Entrez Gene | |||||
Summary |
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Two alternatively spliced transcript variants have been found for this gene, and they encode distinct isoforms. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||
Type | Protein coding | ||||
Genomic Location | Chromosome 20:45684653-45705019 | ||||
Strand | Reverse strand | ||||
Band | q13.12 | ||||
Transcripts |
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Interactions | |||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||
No orthologs found for this gene | |||||
Cross-References | |||||
SwissProt | |||||
TrEMBL | |||||
UniProt Splice Variant | |||||
Entrez Gene | |||||
UniGene | Hs.237392 | ||||
RefSeq | NM_172006 NM_172131 | ||||
HUGO | |||||
OMIM | |||||
CCDS | CCDS13365 CCDS13366 | ||||
HPRD | 15672 | ||||
IMGT | |||||
EMBL | |||||
GenPept | |||||
RNA Seq Atlas | |||||