Homo sapiens Gene: WFDC10B
Summary
InnateDB Gene IDBG-77920.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WFDC10B
Gene Name WAP four-disulfide core domain 10B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000182931
Encoded Proteins
WAP four-disulfide core domain 10B
WAP four-disulfide core domain 10B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Two alternatively spliced transcript variants have been found for this gene, and they encode distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:45684653-45705019
Strand Reverse strand
Band q13.12
Transcripts
ENST00000330523 ENSP00000327628
ENST00000335769 ENSP00000337466
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0030414 peptidase inhibitor activity
Biological Process
GO:0010466 negative regulation of peptidase activity
Cellular Component
GO:0005576 extracellular region
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.237392
RefSeq NM_172006 NM_172131
HUGO
OMIM
CCDS CCDS13365 CCDS13366
HPRD 15672
IMGT
EMBL
GenPept
RNA Seq Atlas