InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RPL37A

Summary

InnateDB Gene

IDBG-80682.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPL37A

Gene Name

ribosomal protein L37a

Synonyms

L37A

Species

Homo sapiens

Ensembl Gene

ENSG00000197756

Encoded Proteins

IDBP-388829

ribosomal protein L37a

IDBP-388831

ribosomal protein L37a

IDBP-388832

ribosomal protein L37a

IDBP-755607

IDBP-755505

IDBP-484485

ribosomal protein L37a

IDBP-755489

IDBP-755466

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37AE family of ribosomal proteins. It is located in the cytoplasm. The protein contains a C4-type zinc finger-like domain. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:216498189-216579180

Strand

Forward strand

Band

q35

Transcripts

ENST00000359681
ENST00000446558	ENSP00000388690
ENST00000420712	ENSP00000410080
ENST00000456586	ENSP00000410240
ENST00000441179	ENSP00000471102
ENST00000427280	ENSP00000472653
ENST00000491306	ENSP00000418082
ENST00000490649
ENST00000478153
ENST00000487233
ENST00000598925	ENSP00000469607
ENST00000600880	ENSP00000470348
ENST00000624436

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 95 experimentally validated interaction(s) in this database.

Experimentally validated
Total	95 [view]
Protein-Protein	94 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003735	structural constituent of ribosome
GO:0044822	poly(A) RNA binding
GO:0046872	metal ion binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0070062	extracellular vesicular exosome