Homo sapiens Gene: FBXL16
Summary
InnateDB Gene IDBG-8109.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXL16
Gene Name F-box and leucine-rich repeat protein 16
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000127585
Encoded Proteins
F-box and leucine-rich repeat protein 16
F-box and leucine-rich repeat protein 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the F-box protein family, such as FBXL16, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:692498-705829
Strand Reverse strand
Band p13.3
Transcripts
ENST00000324361 ENSP00000318674
ENST00000397621 ENSP00000380746
ENST00000562563 ENSP00000455217
ENST00000562585
ENST00000562648
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.513244
RefSeq NM_153350 XM_005255132
HUGO
OMIM
CCDS CCDS10421
HPRD 12365
IMGT
EMBL
GenPept
RNA Seq Atlas