Version 5.4
Homo sapiens Gene: SGCZ
Summary
InnateDB Gene IDBG-8120.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SGCZ
Gene Name sarcoglycan, zeta
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000185053
Encoded Proteins
IDBP-8122
sarcoglycan, zeta
IDBP-361285
sarcoglycan, zeta
IDBP-809969
sarcoglycan, zeta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:14089864-15238339
Strand Reverse strand
Band p22
Transcripts
ENST00000382080 ENSP00000371512
ENST00000421524 ENSP00000405224
ENST00000613692 ENSP00000481839
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0046716 muscle cell cellular homeostasis
GO:0055001 muscle cell development
GO:0061024 membrane organization
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0016012 sarcoglycan complex
GO:0016021 integral component of membrane
GO:0042383 sarcolemma
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000039539
View Gene Order
Cross-References
SwissProt
TrEMBL Q08AT0
UniProt Splice Variant
Entrez Gene 137868
UniGene Hs.676196
RefSeq NM_139167
HUGO HGNC:14075
OMIM 608113
CCDS CCDS5992
HPRD 12165
IMGT
EMBL AC009898 AC019215 AC020992 AC021760 AC022039 AC023538 AC040926 AC084838 AC106857 AC107965 BC125037
GenPept AAI25038
RNA Seq Atlas 137868

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca