Version 5.4
Homo sapiens Gene: SALL4
Summary
InnateDB Gene IDBG-81299.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SALL4
Gene Name sal-like 4 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000101115
Encoded Proteins
IDBP-81301
sal-like 4 (Drosophila)
IDBP-81303
sal-like 4 (Drosophila)
IDBP-238418
sal-like 4 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene may be a zinc finger transcription factor. Defects in this gene are a cause of Duane-radial ray syndrome (DRRS). [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:51784042-51802520
Strand Reverse strand
Band q13.2
Transcripts
ENST00000217086 ENSP00000217086
ENST00000371539 ENSP00000360594
ENST00000395997 ENSP00000379319
ENST00000483130
ENST00000481363
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 52 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 52 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001701 in utero embryonic development
GO:0001833 inner cell mass cell proliferation
GO:0001843 neural tube closure
GO:0003281 ventricular septum development
GO:0006351 transcription, DNA-templated
GO:0007507 heart development
GO:0009888 tissue development
GO:0019827 stem cell maintenance
GO:0021915 neural tube development
GO:0030326 embryonic limb morphogenesis
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0000792 heterochromatin
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0043234 protein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027547
View Gene Order
ENSBTAG00000003101
Not yet available
Pathways
NETPATH
REACTOME
REACT_111045
Developmental Biology pathway
REACT_200812
Transcriptional regulation of pluripotent stem cells pathway
KEGG
INOH
PID NCI
betacatenin_nuc_pathway
Regulation of nuclear beta catenin signaling and target gene transcription
Cross-References
SwissProt Q9UJQ4
TrEMBL
UniProt Splice Variant
Entrez Gene 57167
UniGene Hs.517113
RefSeq NM_020436 XM_005260467 XM_006723834 XM_006723835
HUGO HGNC:15924
OMIM 607343
CCDS CCDS13438
HPRD 08458
IMGT
EMBL AL034420 AY170621 AY172738 BC111714 CH471077
GenPept AAI11715 AAO16566 AAO44950 CAB61485 EAW75595
RNA Seq Atlas 57167

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca