Version 5.4
Homo sapiens Gene: IFIT5
Summary
InnateDB Gene IDBG-81992.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IFIT5
Gene Name interferon-induced protein with tetratricopeptide repeats 5
Synonyms P58; RI58
Species Homo sapiens
Ensembl Gene ENSG00000152778
Encoded Proteins
IDBP-81994
interferon-induced protein with tetratricopeptide repeats 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 26334375
IFIT5 is a positive regulator in IKK phosphorylation and NF-κB activation.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:89414586-89421001
Strand Forward strand
Band q23.31
Transcripts
ENST00000371795 ENSP00000360860
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 24 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003727 single-stranded RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0045087 innate immune response (InnateDB)
GO:0051607 defense response to virus
Cellular Component
GO:0015629 actin cytoskeleton
GO:0032587 ruffle membrane
GO:0045177 apical part of cell
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.252839 Hs.633385
RefSeq NM_012420
HUGO
OMIM
CCDS CCDS7403
HPRD 17130
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca