Version 5.4
Homo sapiens Gene: MOGAT1
Summary
InnateDB Gene IDBG-82211.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MOGAT1
Gene Name monoacylglycerol O-acyltransferase 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000124003
Encoded Proteins
IDBP-389122
monoacylglycerol O-acyltransferase 1
IDBP-810673
monoacylglycerol O-acyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerols, the precursor of physiologically important lipids such as triacylglycerol and phospholipids (Yen et al., 2002 [PubMed 12077311]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:222671738-222709930
Strand Forward strand
Band q36.1
Transcripts
ENST00000446656 ENSP00000406674
ENST00000611505 ENSP00000477992
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003846 2-acylglycerol O-acyltransferase activity
GO:0004144 diacylglycerol O-acyltransferase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
Biological Process
GO:0006071 glycerol metabolic process
GO:0006651 diacylglycerol biosynthetic process
GO:0019432 triglyceride biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000012187
View Gene Order
ENSBTAG00000008431
Not yet available
Cross-References
SwissProt Q96PD6
TrEMBL
UniProt Splice Variant
Entrez Gene 116255
UniGene Hs.344090
RefSeq NM_058165 XM_005246272
HUGO HGNC:18210
OMIM 610268
CCDS CCDS46524
HPRD
IMGT
EMBL AC104772 AF384163 BN000154
GenPept AAK84178 AAX81987 CAD89265
RNA Seq Atlas 116255

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca