Homo sapiens Gene: AP1S3

Summary
InnateDB Gene IDBG-82268.5
Last Modified 2012-02-14   [Report errors or provide feedback]
Gene Symbol AP1S3
Gene Name adaptor-related protein complex 1, sigma 3 subunit
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000152056
Encoded Proteins
IDBP-82272 adaptor-related protein complex 1, sigma 3 subunit
IDBP-237052 adaptor-related protein complex 1, sigma 3 subunit
IDBP-237054 adaptor-related protein complex 1, sigma 3 subunit
IDBP-292981 adaptor-related protein complex 1, sigma 3 subunit
IDBP-389132 adaptor-related protein complex 1, sigma 3 subunit
IDBP-389133 adaptor-related protein complex 1, sigma 3 subunit
IDBP-389134 adaptor-related protein complex 1, sigma 3 subunit
IDBP-389135 adaptor-related protein complex 1, sigma 3 subunit
IDBP-389136 adaptor-related protein complex 1, sigma 3 subunit
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2: 224616403-224702744
Strand Reverse strand
Band q36.1
Transcripts
ENST00000334271  ENSP00000333888
ENST00000396654  ENSP00000379891
ENST00000396653  ENSP00000379890
ENST00000409375  ENSP00000387199
ENST00000443700  ENSP00000397155
ENST00000415298  ENSP00000401705
ENST00000446015  ENSP00000388738
ENST00000444408  ENSP00000399738
ENST00000423110  ENSP00000406686
Interactions
Number of Interactions   This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein‑Protein  3
[view]
Protein‑DNA 0
Protein‑RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
 
Gene Ontology
Accession GO Term
Molecular Function
GO:0008565 protein transporter activity
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0006892 post-Golgi vesicle-mediated transport
GO:0006897 endocytosis
GO:0015031 protein transport
GO:0016032 viral reproduction
GO:0016044 cellular membrane organization
GO:0016192 vesicle-mediated transport
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0050690 regulation of defense response to virus by virus
Cellular Component
GO:0000139 Golgi membrane
GO:0005765 lysosomal membrane
GO:0005829 cytosol
GO:0005905 coated pit
GO:0030117 membrane coat
GO:0030659 cytoplasmic vesicle membrane
GO:0032588 trans-Golgi network membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID Gene Order Method Confidence Comments
ENSMUSG00000054702 Ortholuge SSD Ortholog Ortholog supports species divergence
ENSBTAG00000011133 Not yet available Ortholuge SSD Ortholog Ortholog supports species divergence
Pathways
NETPATH
REACTOME
REACT_19400 Golgi Associated Vesicle Biogenesis
REACT_19287 Lysosome Vesicle Biogenesis
REACT_121399 MHC class II antigen presentation
REACT_11103 Nef mediated downregulation of MHC class I complex cell surface expression
KEGG
hsa04142  Lysosome
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q96PC3 
TrEMBL B8ZZZ1 C9JZK4 F8W8K9 G5E966 Q53R44 Q53T10
UniProt Splice Variant
Entrez Gene 130340 
UniGene
RefSeq NM_001039569 
HUGO 18971 
OMIM
CCDS CCDS42827 
HPRD 16495
IMGT
EMBL AC012512 AC093884 AF393369 AK299026 BC009606 BC021898 CH471063
GenPept AAH09606  AAH21898  AAL09586  AAY24166  AAY24244  BAG61103  EAW70814 
ImmGen AP1S3 (murine) 
RNA Seq Atlas 130340