Homo sapiens Gene: AP1S3
Summary
InnateDB Gene IDBG-82268.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol AP1S3
Gene Name adaptor-related protein complex 1, sigma 3 subunit
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000152056
Encoded Proteins
adaptor-related protein complex 1, sigma 3 subunit
adaptor-related protein complex 1, sigma 3 subunit
adaptor-related protein complex 1, sigma 3 subunit
adaptor-related protein complex 1, sigma 3 subunit
adaptor-related protein complex 1, sigma 3 subunit
adaptor-related protein complex 1, sigma 3 subunit
adaptor-related protein complex 1, sigma 3 subunit
adaptor-related protein complex 1, sigma 3 subunit
adaptor-related protein complex 1, sigma 3 subunit
Protein Structure
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:224616403-224702744
Strand Reverse strand
Band q36.1
Transcripts
ENST00000334271 ENSP00000333888
ENST00000396654 ENSP00000379891
ENST00000396653 ENSP00000379890
ENST00000409375 ENSP00000387199
ENST00000443700 ENSP00000397155
ENST00000415298 ENSP00000401705
ENST00000446015 ENSP00000388738
ENST00000444408 ENSP00000399738
ENST00000423110 ENSP00000406686
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008565 protein transporter activity
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0006892 post-Golgi vesicle-mediated transport
GO:0006897 endocytosis
GO:0015031 protein transport
GO:0016032 viral reproduction
GO:0016044 cellular membrane organization
GO:0016192 vesicle-mediated transport
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0050690 regulation of defense response to virus by virus
Cellular Component
GO:0000139 Golgi membrane
GO:0005765 lysosomal membrane
GO:0005829 cytosol
GO:0005905 coated pit
GO:0030117 membrane coat
GO:0030659 cytoplasmic vesicle membrane
GO:0032588 trans-Golgi network membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
MHC class II antigen presentation pathway
Nef mediated downregulation of MHC class I complex cell surface expression pathway
Lysosome Vesicle Biogenesis pathway
Golgi Associated Vesicle Biogenesis pathway
KEGG
Lysosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q96PC3
TrEMBL B8ZZZ1 C9JZK4 F8W8K9 G5E966 Q53R44 Q53T10
UniProt Splice Variant
Entrez Gene 130340
UniGene
RefSeq NM_001039569
HUGO 18971
OMIM
CCDS CCDS42827
HPRD 16495
IMGT
EMBL AC012512 AC093884 AF393369 AK299026 BC009606 BC021898 CH471063
GenPept AAH09606 AAH21898 AAL09586 AAY24166 AAY24244 BAG61103 EAW70814
ImmGen AP1S3 (murine)
RNA Seq Atlas 130340