Version 5.4
Homo sapiens Gene: MNF1
Summary
InnateDB Gene IDBG-83199.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MNF1
Gene Name mitochondrial nucleoid factor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000137288
Encoded Proteins
IDBP-83201
chromosome 6 open reading frame 125
IDBP-83203
chromosome 6 open reading frame 125
IDBP-807852
ubiquinol-cytochrome c reductase complex assembly factor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a nucleoid protein localized to the mitochondria inner membrane. The encoded protein affects regulation of insulin secretion, mitochondrial ATP production, and myogenesis through modulation of mitochondrial respiratory chain activity. [provided by RefSeq, Oct 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:33694293-33711727
Strand Reverse strand
Band p21.31
Transcripts
ENST00000374231 ENSP00000363348
ENST00000374214 ENSP00000363331
ENST00000606961
ENST00000607484 ENSP00000476140
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0002082 regulation of oxidative phosphorylation
GO:0050796 regulation of insulin secretion
GO:2001014 regulation of skeletal muscle cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005758 mitochondrial intermembrane space
GO:0005759 mitochondrial matrix
GO:0042645 mitochondrial nucleoid
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000024208
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 84300
UniGene
RefSeq NM_032340
HUGO HGNC:21237
OMIM 614461
CCDS CCDS4784
HPRD 12847
IMGT
EMBL
GenPept
RNA Seq Atlas 100500873 84300

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca