Homo sapiens Gene: NEU2 | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-83431.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | NEU2 | ||||||||||
Gene Name | sialidase 2 (cytosolic sialidase) | ||||||||||
Synonyms | SIAL2 | ||||||||||
Species | Homo sapiens | ||||||||||
Ensembl Gene | ENSG00000115488 | ||||||||||
Encoded Proteins |
sialidase 2 (cytosolic sialidase)
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 2:233032672-233035057 | ||||||||||
Strand | Forward strand | ||||||||||
Band | q37.1 | ||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||
NETPATH | |||||||||||
REACTOME |
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
Glycosphingolipid metabolism pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Sialic acid metabolism pathway
Metabolism of proteins pathway
Metabolism pathway
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KEGG |
Sphingolipid metabolism pathway
Other glycan degradation pathway
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INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | Q9Y3R4 | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 4759 | ||||||||||
UniGene | Hs.532681 | ||||||||||
RefSeq | NM_005383 | ||||||||||
HUGO | HGNC:7759 | ||||||||||
OMIM | 605528 | ||||||||||
CCDS | CCDS2501 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | AC106876 BC069151 BC107053 CH471063 Y16535 | ||||||||||
GenPept | AAH69151 AAI07054 AAY24360 CAB41449 EAW71028 | ||||||||||
RNA Seq Atlas | 4759 | ||||||||||