Version 5.4
Homo sapiens Gene: PPP1R3D
Summary
InnateDB Gene IDBG-83631.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R3D
Gene Name protein phosphatase 1, regulatory subunit 3D
Synonyms PPP1R6
Species Homo sapiens
Ensembl Gene ENSG00000132825
Encoded Proteins
IDBP-83633
protein phosphatase 1, regulatory subunit 3D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Phosphorylation of serine and threonine residues in proteins is a crucial step in the regulation of many cellular functions ranging from hormonal regulation to cell division and even short-term memory. The level of phosphorylation is controlled by the opposing actions of protein kinases and protein phosphatases. Protein phosphatase 1 (PP1) is 1 of 4 major serine/threonine-specific protein phosphatases which have been identified in eukaryotic cells. PP1 associates with various regulatory subunits that dictate its subcellular localization and modulate its substrate specificity. Several subunits that target PP1 to glycogen have been identified. This gene encodes a glycogen-targeting subunit of PP1. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:59936668-59940297
Strand Reverse strand
Band q13.33
Transcripts
ENST00000370996 ENSP00000360035
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 7 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004721 phosphoprotein phosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0005515 protein binding
GO:0019899 enzyme binding
Biological Process
GO:0005977 glycogen metabolic process
GO:0005979 regulation of glycogen biosynthetic process
GO:0005981 regulation of glycogen catabolic process
GO:0016311 dephosphorylation
Cellular Component
GO:0042587 glycogen granule
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000049999
View Gene Order
ENSBTAG00000027397
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04910
Insulin signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt O95685
TrEMBL
UniProt Splice Variant
Entrez Gene 5509
UniGene Hs.42215 Hs.662831
RefSeq NM_006242
HUGO HGNC:9294
OMIM 603326
CCDS CCDS13483
HPRD 04507
IMGT
EMBL AL109928 BC074860 BC074861 Y18206
GenPept AAH74860 AAH74861 CAA77081 CAB92096
RNA Seq Atlas 5509

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca