InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RPL39

Summary

InnateDB Gene

IDBG-83967.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPL39

Gene Name

ribosomal protein L39

Synonyms

L39; RPL39_23_1806; RPL39P42

Species

Homo sapiens

Ensembl Gene

ENSG00000198918

Encoded Proteins

IDBP-83969

ribosomal protein L39

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the S39E family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein is the smallest, and one of the most basic, proteins of the ribosome. This gene is co-transcribed with the U69 small nucleolar RNA gene, which is located in its second intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:119786504-119791643

Strand

Reverse strand

Band

q24

Transcripts

ENST00000361575	ENSP00000355315
ENST00000477403
ENST00000468844

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0002227	innate immune response in mucosa
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0019731	antibacterial humoral response
GO:0044267	cellular protein metabolic process
GO:0050830	defense response to Gram-positive bacterium