Version 5.4
Homo sapiens Gene: GTPBP5
Summary
InnateDB Gene IDBG-84113.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GTPBP5
Gene Name GTP binding protein 5 (putative)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000101181
Encoded Proteins
IDBP-84119
GTP binding protein 5 (putative)
IDBP-380114
GTP binding protein 5 (putative)
IDBP-585351
GTP binding protein 5 (putative)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Small G proteins, such as GTPBP5, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction (Hirano et al., 2006 [PubMed 17054726]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:62183029-62203568
Strand Forward strand
Band q13.33
Transcripts
ENST00000370823 ENSP00000359859
ENST00000448254 ENSP00000414693
ENST00000466933
ENST00000471352
ENST00000467101 ENSP00000435214
ENST00000472005
ENST00000466099
ENST00000461411
ENST00000471962
ENST00000488748
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0015093 ferrous iron transmembrane transporter activity
Biological Process
GO:0006184 GTP catabolic process
GO:0015684 ferrous iron transport
GO:0042254 ribosome biogenesis
GO:0044065 regulation of respiratory system process
GO:0070129 regulation of mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005761 mitochondrial ribosome
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039069
View Gene Order
ENSBTAG00000014442
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.713336 Hs.733011 Hs.733574
RefSeq NM_015666 XM_005260393 XM_006723772 XM_006723773 XM_006723774 XM_006723775
HUGO
OMIM
CCDS CCDS13492
HPRD 13617
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca