Version 5.4
Homo sapiens Gene: RAB17
Summary
InnateDB Gene IDBG-84300.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAB17
Gene Name RAB17, member RAS oncogene family
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000124839
Encoded Proteins
IDBP-84302
RAB17, member RAS oncogene family
IDBP-246550
RAB17, member RAS oncogene family
IDBP-292860
RAB17, member RAS oncogene family
IDBP-292863
RAB17, member RAS oncogene family
IDBP-389479
RAB17, member RAS oncogene family
IDBP-389480
RAB17, member RAS oncogene family
IDBP-389481
RAB17, member RAS oncogene family
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase (Lutcke et al., 1993 [PubMed 8486736]).[supplied by OMIM, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:237574322-237601614
Strand Reverse strand
Band q37.3
Transcripts
ENST00000264601 ENSP00000264601
ENST00000392001 ENSP00000375858
ENST00000409576 ENSP00000386792
ENST00000409822 ENSP00000386589
ENST00000414278 ENSP00000389332
ENST00000411462 ENSP00000400240
ENST00000430445 ENSP00000401495
ENST00000416106
ENST00000477149
ENST00000466244
ENST00000487008
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019003 GDP binding
Biological Process
GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0032401 establishment of melanosome localization
GO:0032402 melanosome transport
GO:0032456 endocytic recycling
GO:0045056 transcytosis
GO:0046847 filopodium assembly
GO:0050773 regulation of dendrite development
GO:0051489 regulation of filopodium assembly
GO:0051963 regulation of synapse assembly
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0030425 dendrite
GO:0042470 melanosome
GO:0043025 neuronal cell body
GO:0055037 recycling endosome
GO:0055038 recycling endosome membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026304
View Gene Order
ENSBTAG00000017624
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.44278 Hs.690384
RefSeq NM_022449 XM_006712689
HUGO
OMIM
CCDS CCDS2520
HPRD 11468
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca