Version 5.4
Homo sapiens Gene: ARPC5L
Summary
InnateDB Gene IDBG-85023.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARPC5L
Gene Name actin related protein 2/3 complex, subunit 5-like
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000136950
Encoded Proteins
IDBP-85025
actin related protein 2/3 complex, subunit 5-like
IDBP-85027
actin related protein 2/3 complex, subunit 5-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 9:124862130-124877733
Strand Forward strand
Band q33.3
Transcripts
ENST00000353214 ENSP00000345361
ENST00000259477 ENSP00000259477
ENST00000465124
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003779 actin binding
Biological Process
GO:0008150 biological_process
GO:0030833 regulation of actin filament polymerization
GO:0034314 Arp2/3 complex-mediated actin nucleation
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005885 Arp2/3 protein complex
GO:0015629 actin cytoskeleton
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026755
View Gene Order
ENSBTAG00000015278
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa05130
Pathogenic Escherichia coli infection pathway
hsa04666
Fc gamma R-mediated phagocytosis pathway
hsa05100
Bacterial invasion of epithelial cells pathway
hsa05131
Shigellosis pathway
INOH
PID NCI
Cross-References
SwissProt Q9BPX5
TrEMBL A0A024R897
UniProt Splice Variant
Entrez Gene 81873
UniGene Hs.694027
RefSeq XM_005252250 NM_030978
HUGO HGNC:23366
OMIM
CCDS CCDS6859
HPRD 12490
IMGT
EMBL AF087842 AL354928 BC000018 BC000798 BC002418 CH471090
GenPept AAH00018 AAH00798 AAH02418 AAP97155 CAI39641 EAW87603 EAW87604
RNA Seq Atlas 81873

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca